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Company	Category	Region	Status	Sources	Links
OnebriefOnebrief makes military headquarters run seamlessly	OtherUses AI	Honolulu, HI, USA; Remote		Docs	Open homepage
OneCLIThe open source AI teammates for your company.	AI infraUses AI	San Francisco, CA, USA		Docs	Open homepage
OnePatchAutomate on-call at agent-scale.	AI infraUses AI	San Francisco, CA, USA		Docs	Open homepage
OneSignalEngage customers through personalized omni-channel messaging	OtherUses AI	San Francisco, CA, USA		Docs	Open homepage
OneStopThe local internet for NYC.	VerticalUses AI	New York City, NY, USA		Docs	Open homepage
OneTextFrictionless payments via SMS	OtherUses AI	San Francisco, CA, USA; Remote		Docs	Open homepage
OntopSimplifying hiring and payments for the global workforce	OtherUses AI	Miami, FL, USA; Remote		Docs	Open homepage
Opalite HealthHelping Healthcare Providers Speak Any Language	OtherUses AI	San Francisco, CA, USA		Docs	Open homepage
Open ActuationQuick-turn, purpose-built motors & actuators for all	RoboticsUses AI	Los Angeles, CA, USA		Docs	Open homepage
OpenHackAlways-on AI security engineer	VerticalUses AI	San Francisco, CA, USA		Docs	Open homepage
OpenProseAn open-source operating system for reliable long-running agents	OtherUses AI	Boston, MA, USA; Remote		Docs	Open homepage
OpenReplayOpen-source, self-hosted, session replay tool for developers.	OtherUses AI	New York City, NY, USA; Paris, Île-de-France, France		Docs	Open homepage
OpenSeaThis isn't just a marketplace; we're shaping the future of digital…	OtherUses AI	New York City, NY, USA; Remote		Docs	Open homepage
OpenSEOOpen source alternative to Semrush and Ahrefs	OtherUses AI	Boston, MA, USA		Docs	Open homepage
OpenTagModel Agnostic AI coworker in Slack	AI infraUses AI	San Francisco, CA, USA		Docs	Open homepage
OpentronsWe make robots for biologists.	RoboticsUses AI	New York City, NY, USA; New York, NY, USA		Docs	Open homepage
OpenWorkThe open source alternative to Claude Cowork	OtherUses AI	San Francisco, CA, USA		Docs	Open homepage
OpenWrenchWe help retailers and restaurant chains manage repairs and…	OtherUses AI	San Francisco, CA, USA		Docs	Open homepage
OpEraAutomated operations research (OR) lab	VerticalUses AI	New York City, NY, USA		Docs	Open homepage
OperandDue diligence and value-creation tools using quantitative methods and AI for private equity firms.	OtherUses AI	San Francisco, CA, USA		Docs	Open homepage
OperonAgentic data layer for manufacturing & process industries.	AI infraUses AI	San Francisco, CA, USA		Docs	Open homepage
OpheliaMedication & support to beat opioid addiction from home	OtherUses AI	New York City, NY, USA; New York, NY, USA		Docs	Open homepage
Orange SliceAgentic sales enrichment spreadsheet	OtherUses AI	San Francisco, CA, USA		Docs	Open homepage
Orbital OperationsHigh Thrust Space Vehicles for Satellite Defense	OtherUses AI	Los Angeles, CA, USA		Docs	Open homepage

Staff list a company once its homepage loads and one to three sources back it up. Map pins use a sourced city or region — near that place or at the region centroid. Unknown location stays list-only. Founders, exit, and jobs stay omitted unless sourced. Founder photos stay omitted unless a sourced URL is listed — we never invent a face. We do not invent people, a street address, or size, price, or growth figures.