Startups worth watching

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Company	Category	Region	Status	Sources	Links
ManifoldDrop-in robotic labor that works on Day 1	RoboticsUses AI	Los Angeles, CA, USA		Docs	Open homepage
MantisDigital Twins of humans	OtherUses AI	New York City, NY, USA		Docs	Open homepage
Maple MaterialsWe turn CO2 into battery-grade graphite and oxygen.	OtherUses AI	San Francisco, CA, USA		Docs	Open homepage
Maquoketa ResearchAutomated LiveOps for Game Studios	OtherUses AI	San Francisco, CA, USA		Docs	Open homepage
MarengoAI-Native Engineering Firm designing Data Centers	EnergyUses AI	San Francisco, CA, USA		Docs	Open homepage
MarginPOS & operating system that makes liquor stores more money	OtherUses AI	New York City, NY, USA		Docs	Open homepage
MaritimeThe managed cloud for AI agents.	OtherUses AI	San Francisco, CA, USA		Docs	Open homepage
Maritime FusionFusion reactors for ships	EnergyUses AI	San Francisco, CA, USA		Docs	Open homepage
Mark Cuban Cost Plus Drug Company, PBCMaking low cost versions of high cost generic drugs.	OtherUses AI	Dallas, TX, USA		Docs	Open homepage
MarkhorMarkhor is a DTC company that works with craftsmen to make shoes and…	OtherUses AI	San Francisco, CA, USA; Remote		Docs	Open homepage
MasonMason is the fastest way to take smart devices from idea to end user	OtherUses AI	Seattle, WA, USA		Docs	Open homepage
Mass MagneticsUSA-made magnetics for robotics and defense.	RoboticsUses AI	Boston, MA, USA		Docs	Open homepage
MassdriverInternal developer platform for Terraform, OpenTofu and Helm	OtherUses AI	Los Angeles, CA, USA; Remote		Docs	Open homepage
MasterpieceWorking capital for data companies training frontier AI	VerticalUses AI	New York City, NY, USA		Docs	Open homepage
MatanoCloud Native SIEM (alternative to Splunk/Elastic)	OtherUses AI	Seattle, WA, USA; San Francisco, CA, USA		Docs	Open homepage
MatrubialsDeveloping milk-inspired therapeutics for infectious diseases	VerticalUses AI	Davis, CA, USA		Docs	Open homepage
MatterBuilding the future of reading	OtherUses AI	San Francisco, CA, USA; Remote		Docs	Open homepage
MattermostSecure Collaboration for Technical Teams	OtherUses AI	San Francisco, CA, USA; Palo Alto, CA, USA; Remote		Docs	Open homepage
MavenPayments for Conversational Agents	OtherUses AI	San Francisco, CA, USA		Docs	Open homepage
MaverickXEngineering the future of chemistry for natural resource extraction	EnergyUses AI	Austin, TX, USA		Docs	Open homepage
MayanA growth automation platform for Amazon sellers	OtherUses AI	Las Vegas, NV, USA; Remote		Docs	Open homepage
MaywoodThe first finance-compliant proactive AI that runs 24/7	OtherUses AI	New York City, NY, USA		Docs	Open homepage
MeadowPoint of Sale and Compliance SaaS for Cannabis Dispensaries	OtherUses AI	San Francisco, CA, USA		Docs	Open homepage
MeasuredTelemedicine platform for chronic conditions like obesity	OtherUses AI	New York City, NY, USA; New York, NY, USA		Docs	Open homepage

Staff list a company once its homepage loads and one to three sources back it up. Map pins use a sourced city or region — near that place or at the region centroid. Unknown location stays list-only. Founders, exit, and jobs stay omitted unless sourced. Founder photos stay omitted unless a sourced URL is listed — we never invent a face. We do not invent people, a street address, or size, price, or growth figures.